diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 05d93832..7b149615 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -76,7 +76,7 @@ jobs:
       fail-fast: false # If one platform fails, allow the rest to keep testing.
       matrix:
         rust: [stable]
-        python-version: [3.6, 3.7, 3.8, 3.9, "3.10", pypy-3.6, pypy-3.7]
+        python-version: [3.6, 3.7, 3.8, 3.9, "3.10", pypy-3.6, pypy-3.7, pypy-3.8]
         platform:
           [
             {
@@ -110,6 +110,8 @@ jobs:
           # PyPy 3.7 on Windows doesn't release 32-bit builds any more
           - python-version: pypy-3.7
             platform: { os: "windows-latest", python-architecture: "x86" }
+          - python-version: pypy-3.8
+            platform: { os: "windows-latest", python-architecture: "x86" }
         include:
           # PyPy3.6 still runs on macos-10.15
           - rust: stable
diff --git a/CHANGELOG.md b/CHANGELOG.md
index e32c23ad..a78ee55b 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -13,6 +13,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - Support Python 3.10. [#1889](https://github.com/PyO3/pyo3/pull/1889)
 - Added optional `eyre` feature to convert `eyre::Report` into `PyErr`. [#1893](https://github.com/PyO3/pyo3/pull/1893)
 - Added optional `anyhow` feature to convert `anyhow::Error` into `PyErr`. [#1822](https://github.com/PyO3/pyo3/pull/1822)
+- Support PyPy 3.8. [#1948](https://github.com/PyO3/pyo3/pull/1948)
 
 ### Added
 
diff --git a/src/ffi/datetime.rs b/src/ffi/datetime.rs
index 749286d8..8510b96e 100644
--- a/src/ffi/datetime.rs
+++ b/src/ffi/datetime.rs
@@ -361,7 +361,7 @@ pub struct PyDateTime_CAPI {
     pub TimeType: *mut PyTypeObject,
     pub DeltaType: *mut PyTypeObject,
     pub TZInfoType: *mut PyTypeObject,
-    #[cfg(all(Py_3_7, not(PyPy)))]
+    #[cfg(all(Py_3_7, any(not(PyPy), Py_3_8)))]
     pub TimeZone_UTC: *mut PyObject,
     pub Date_FromDate: unsafe extern "C" fn(
         year: c_int,
@@ -395,7 +395,7 @@ pub struct PyDateTime_CAPI {
         normalize: c_int,
         cls: *mut PyTypeObject,
     ) -> *mut PyObject,
-    #[cfg(all(Py_3_7, not(PyPy)))]
+    #[cfg(all(Py_3_7, any(not(PyPy), Py_3_8)))]
     pub TimeZone_FromTimeZone:
         unsafe extern "C" fn(offset: *mut PyObject, name: *mut PyObject) -> *mut PyObject,
 
@@ -451,7 +451,7 @@ pub static PyDateTimeAPI: _PyDateTimeAPI_impl = _PyDateTimeAPI_impl {
 ///
 /// The type obtained by dereferencing this object is `&'static PyObject`. This may change in the
 /// future to be a more specific type representing that this is a `datetime.timezone` object.
-#[cfg(all(Py_3_7, not(PyPy)))]
+#[cfg(all(Py_3_7, any(not(PyPy), Py_3_8)))]
 pub static PyDateTime_TimeZone_UTC: _PyDateTime_TimeZone_UTC_impl = _PyDateTime_TimeZone_UTC_impl {
     inner: &PyDateTimeAPI,
 };
@@ -609,12 +609,12 @@ impl Deref for _PyDateTimeAPI_impl {
 }
 
 #[doc(hidden)]
-#[cfg(all(Py_3_7, not(PyPy)))]
+#[cfg(all(Py_3_7, any(not(PyPy), Py_3_8)))]
 pub struct _PyDateTime_TimeZone_UTC_impl {
     inner: &'static _PyDateTimeAPI_impl,
 }
 
-#[cfg(all(Py_3_7, not(PyPy)))]
+#[cfg(all(Py_3_7, any(not(PyPy), Py_3_8)))]
 impl Deref for _PyDateTime_TimeZone_UTC_impl {
     type Target = crate::PyObject;
 
@@ -661,7 +661,7 @@ mod tests {
     }
 
     #[test]
-    #[cfg(all(Py_3_7, not(PyPy)))]
+    #[cfg(all(Py_3_7, any(not(PyPy), Py_3_8)))]
     fn test_utc_timezone() {
         Python::with_gil(|py| {
             let utc_timezone = PyDateTime_TimeZone_UTC.as_ref(py);